PAK6 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Cell lysate)
PAK6 MaxPab rabbit polyclonal antibody. Western Blot analysis of PAK6 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of PAK6 expression in transfected 293T cell line (H00056924-T02) by PAK6 MaxPab polyclonal antibody.
Lane 1: PAK6 transfected lysate(74.90 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PAK6 on HeLa cell. [antibody concentration 20 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PAK6 protein.
Immunogen
PAK6 (NP_064553.1, 1 a.a. ~ 681 a.a) full-length human protein.
Sequence
MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRITRVQLQPMKTVVRGSAMPVDGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLGLLGDEHWATDPDMYLQSPQSERTDPHGLYLSCNGGTPAGHKQMPWPEPQSPRVLPNGLAAKAQSLGPAEFQGASQRCLQLGACLQSSPPGASPPTGTNRHGMKAAKHGSEEARPQSCLVGSATGRPGGEGSPSPKTRESSLKRRLFRSMFLSTAATAPPSSSKPGPPPQSKPNSSFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQKSLRTAPATGQLPGRSSPAGSPRTWHAQISTSNLYLPQDPTVAKGALAGEDTGVVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PAK6 MaxPab rabbit polyclonal antibody. Western Blot analysis of PAK6 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of PAK6 expression in transfected 293T cell line (H00056924-T02) by PAK6 MaxPab polyclonal antibody.
Lane 1: PAK6 transfected lysate(74.90 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PAK6 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — PAK6
Entrez GeneID
56924GeneBank Accession#
NM_020168.3Protein Accession#
NP_064553.1Gene Name
PAK6
Gene Alias
PAK5
Gene Description
p21 protein (Cdc42/Rac)-activated kinase 6
Omim ID
608110Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
p21(CDKN1A)-activated kinase 6|p21-activated kinase 6|p21-activated protein kinase 6
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Interactome
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Pathway
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Disease
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