CFC1 monoclonal antibody (M09), clone 2G4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CFC1.
Immunogen
CFC1 (NP_115934.1, 27 a.a. ~ 93 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QREKHNGGREEVTKVATQKHRQSPLNWTSSHFGEVTGSAEGWGPEEPLPYSRAFGEGASARPRCCRN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (54); Rat (55)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.11 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of CFC1 transfected lysate using anti-CFC1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with CFC1 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CFC1 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — CFC1
Entrez GeneID
55997GeneBank Accession#
NM_032545Protein Accession#
NP_115934.1Gene Name
CFC1
Gene Alias
CRYPTIC, FLJ77897, HTX2, MGC133213
Gene Description
cripto, FRL-1, cryptic family 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. These proteins play key roles in intercellular signaling pathways during vertebrate embryogenesis. Mutations in this gene can cause autosomal visceral heterotaxy. This protein is involved in left-right asymmetric morphogenesis during organ development. [provided by RefSeq
Other Designations
cryptic
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Interactome
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Disease
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