UNC45A purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Tissue lysate)
UNC45A MaxPab polyclonal antibody. Western Blot analysis of UNC45A expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of UNC45A expression in transfected 293T cell line (H00055898-T02) by UNC45A MaxPab polyclonal antibody.
Lane 1: UNC45A transfected lysate(103.84 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to UNC45A on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human UNC45A protein.
Immunogen
UNC45A (NP_061141, 1 a.a. ~ 944 a.a) full-length human protein.
Sequence
MTVSGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQAVSLAACHLLQVMFDALKEGVKKGFRGKEGAIIVDPARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSLQDPPGELAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKCSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRLEERSVLFAVASALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMVCMVKTESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDELLQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLSSNQELQHRGAVVVLNMVEASREIASTLMESEMMEILSVLAKGDHSPVTRAAAACLDKAVEYGLIQPNQDGE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
UNC45A MaxPab polyclonal antibody. Western Blot analysis of UNC45A expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of UNC45A expression in transfected 293T cell line (H00055898-T02) by UNC45A MaxPab polyclonal antibody.
Lane 1: UNC45A transfected lysate(103.84 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to UNC45A on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — UNC45A
Entrez GeneID
55898GeneBank Accession#
NM_018671Protein Accession#
NP_061141Gene Name
UNC45A
Gene Alias
FLJ10043, GC-UNC45, GCUNC-45, GCUNC45, IRO039700, SMAP-1, SMAP1
Gene Description
unc-45 homolog A (C. elegans)
Omim ID
611219Gene Ontology
HyperlinkGene Summary
UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM
Other Designations
general cell UNC45|smooth muscle cell associated protein-1
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Interactome
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Publication Reference
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Actomyosin dependent cell contractility orchestrates zika virus infection.
Xinyi Huang, Yifan Xing, Yanqin Cui, Baohua Ji, Binbin Ding, Jin Zhong, Yaming Jiu.
Journal of Cell Science 2023 Sep; 136(17):jcs261301.
Application：WB, Human, Monkey, U2OS, VeroE6 cells.
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UNC-45A breaks the microtubule lattice independently of its effects on non-muscle myosin II.
Juri Habicht, Ashley Mooneyham, Asumi Hoshino, Mihir Shetty, Xiaonan Zhang, Edith Emmings, Qing Yang, Courtney Coombes, Melissa K Gardner, Martina Bazzaro.
Journal of Cell Science 2021 Jan; 134(1):jcs248815.
Application：WB-Re, Recombinant proteins.
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Actomyosin dependent cell contractility orchestrates zika virus infection.
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