HDAC8 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human HDAC8 protein.
Immunogen
HDAC8 (NP_060956.1, 1 a.a. ~ 377 a.a) full-length human protein.
Sequence
MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HDAC8 expression in transfected 293T cell line (H00055869-T01) by HDAC8 MaxPab polyclonal antibody.
Lane 1: HDAC8 transfected lysate(41.47 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to HDAC8 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — HDAC8
Entrez GeneID
55869GeneBank Accession#
NM_018486.1Protein Accession#
NP_060956.1Gene Name
HDAC8
Gene Alias
HDACL1, RPD3
Gene Description
histone deacetylase 8
Omim ID
300269Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. [provided by RefSeq
Other Designations
histone deacetylase-like 1
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Interactome
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Disease
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