ST6GALNAC1 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of ST6GALNAC1 expression in transfected 293T cell line (H00055808-T01) by ST6GALNAC1 MaxPab polyclonal antibody.
Lane 1: ST6GALNAC1 transfected lysate(66 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ST6GALNAC1 protein.
Immunogen
ST6GALNAC1 (NP_060884.1, 1 a.a. ~ 600 a.a) full-length human protein.
Sequence
MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGNGGQTRKLTASRTVSEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPFQSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPNLTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (71); Rat (61)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ST6GALNAC1 expression in transfected 293T cell line (H00055808-T01) by ST6GALNAC1 MaxPab polyclonal antibody.
Lane 1: ST6GALNAC1 transfected lysate(66 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ST6GALNAC1
Entrez GeneID
55808GeneBank Accession#
NM_018414.3Protein Accession#
NP_060884.1Gene Name
ST6GALNAC1
Gene Alias
HSY11339, SIAT7A, ST6GalNAcI, STYI
Gene Description
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Omim ID
610138Gene Ontology
HyperlinkGene Summary
Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM
Other Designations
GalNAc alpha-2, 6-sialyltransferase I|GalNAc alpha-2, 6-sialyltransferase I, long form|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase|sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sia
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Interactome
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Pathway
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Disease
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