N4BP2 monoclonal antibody (M01), clone 2H5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant N4BP2.
Immunogen
N4BP2 (NP_060647, 1671 a.a. ~ 1770 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HLAAIEIFEKVNASLLPQNVLDLHGLHVDEALEHLMRVLEKKTEEFKQNGGKPYLSVITGRGNHSQGGVARIKPAVIKYLISHSFRFSEIKPGCLKVMLK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged N4BP2 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — N4BP2
Entrez GeneID
55728GeneBank Accession#
NM_018177Protein Accession#
NP_060647Gene Name
N4BP2
Gene Alias
B3BP, FLJ10680, KIAA1413
Gene Description
NEDD4 binding protein 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. [provided by RefSeq
Other Designations
BCL-3 binding protein|Nedd4 binding protein 2|OTTHUMP00000158757
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