SARS2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SARS2 protein.
Immunogen
SARS2 (NP_060297.1, 1 a.a. ~ 518 a.a) full-length human protein.
Sequence
MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDIERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLAGTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPALQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (86)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SARS2 MaxPab polyclonal antibody. Western Blot analysis of SARS2 expression in human liver.Western Blot (Cell lysate)
SARS2 MaxPab polyclonal antibody. Western Blot analysis of SARS2 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of SARS2 expression in transfected 293T cell line (H00054938-T01) by SARS2 MaxPab polyclonal antibody.
Lane 1: SARS2 transfected lysate(56.98 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SARS2
Entrez GeneID
54938GeneBank Accession#
NM_017827.2Protein Accession#
NP_060297.1Gene Name
SARS2
Gene Alias
FLJ20450, SARS, SARSM, SERS, SYS, SerRSmt, mtSerRS
Gene Description
seryl-tRNA synthetase 2, mitochondrial
Gene Ontology
HyperlinkGene Summary
This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
serine tRNA ligase 2, mitochondrial|serine-tRNA ligase, mitochondrial|seryl-tRNA synthetase 2
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Interactome
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Pathway
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