RNF111 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
RNF111 MaxPab polyclonal antibody. Western Blot analysis of RNF111 expression in rat brain.
Western Blot (Transfected lysate)
Western Blot analysis of RNF111 expression in transfected 293T cell line (H00054778-T01) by RNF111 MaxPab polyclonal antibody.
Lane 1: RNF111 transfected lysate(108.35 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to RNF111 on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RNF111 protein.
Immunogen
RNF111 (AAH60862.1, 1 a.a. ~ 985 a.a) full-length human protein.
Sequence
MSQWTPEYKELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES
Host
Mouse
Reactivity
Human, Rat
Interspecies Antigen Sequence
Mouse (89); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
RNF111 MaxPab polyclonal antibody. Western Blot analysis of RNF111 expression in rat brain.Western Blot (Transfected lysate)
Western Blot analysis of RNF111 expression in transfected 293T cell line (H00054778-T01) by RNF111 MaxPab polyclonal antibody.
Lane 1: RNF111 transfected lysate(108.35 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to RNF111 on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml] -
Gene Info — RNF111
Entrez GeneID
54778GeneBank Accession#
BC060862.1Protein Accession#
AAH60862.1Gene Name
RNF111
Gene Alias
ARK, DKFZp313E0731, DKFZp686H1966, DKFZp761D081, FLJ38008
Gene Description
ring finger protein 111
Omim ID
605840Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. The mouse counterpart of this gene (Rnf111/arkadia) has been shown to genetically interact with the transforming growth factor (TGF) beta-like factor Nodal, and act as a modulator of the nodal signaling cascade, which is essential for the induction of mesoderm during embryonic development. [provided by RefSeq
Other Designations
Arkadia
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Interactome
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Publication Reference
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Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control.
Sun H, Liu Y, Hunter T.
Molecular and Cellular Biology 2014 Aug; 34(16):2981.
Application：WB-Tr, Mouse, MEFs.
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Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling.
Zhou F, Drabsch Y, Dekker TJ, de Vinuesa AG, Li Y, Hawinkels LJ, Sheppard KA, Goumans MJ, Luwor RB, de Vries CJ, Mesker WE, Tollenaar RA, Devilee P, Lu CX, Zhu H, Zhang L, Dijke PT.
Nature Communications 2014 Mar; 5:3388.
Application：WB-Tr, Human, HEK 293T cells.
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Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control.
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