POLE3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human POLE3 full-length ORF ( AAH03166, 1 a.a. - 147 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
41.91
Interspecies Antigen Sequence
Mouse (93); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — POLE3
Entrez GeneID
54107GeneBank Accession#
BC003166Protein Accession#
AAH03166Gene Name
POLE3
Gene Alias
CHARAC17, CHRAC17, YBL1, p17
Gene Description
polymerase (DNA directed), epsilon 3 (p17 subunit)
Omim ID
607267Gene Ontology
HyperlinkGene Summary
POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM
Other Designations
DNA polymerase epsilon p17 subunit|DNA polymerase epsilon subunit 3|OTTHUMP00000021954|OTTHUMP00000021955|arsenic transactivated protein|chromatin accessibility complex 17|histone fold protein CHRAC17
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Interactome
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Pathway
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