PANK1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PANK1 MaxPab polyclonal antibody. Western Blot analysis of PANK1 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of PANK1 expression in transfected 293T cell line (H00053354-T01) by PANK1 MaxPab polyclonal antibody.
Lane1:PANK1 transfected lysate(41.03 KDa).
Lane2:Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PANK1 protein.
Immunogen
PANK1 (NP_683879.1, 1 a.a. ~ 373 a.a) full-length human protein.
Sequence
MKLINGKKQTFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPSCAMHRFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRDSISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELFKMTDDK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (98)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PANK1 MaxPab polyclonal antibody. Western Blot analysis of PANK1 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of PANK1 expression in transfected 293T cell line (H00053354-T01) by PANK1 MaxPab polyclonal antibody.
Lane1:PANK1 transfected lysate(41.03 KDa).
Lane2:Non-transfected lysate.
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Gene Info — PANK1
Entrez GeneID
53354GeneBank Accession#
NM_148978.1Protein Accession#
NP_683879.1Gene Name
PANK1
Gene Alias
MGC24596, PANK, PANK1a, PANK1b
Gene Description
pantothenate kinase 1
Omim ID
606160Gene Ontology
HyperlinkGene Summary
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000020071|OTTHUMP00000020072|pantothenic acid kinase
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Pathway
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Disease
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Publication Reference
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Regulation of the CoA Biosynthetic Complex Assembly in Mammalian Cells.
Jovana Baković, David López Martínez, Savvas Nikolaou, Bess Yi Kun Yu, Maria-Armineh Tossounian, Yugo Tsuchiya, Christopher Thrasivoulou, Valeriy Filonenko, Ivan Gout.
International Journal of Molecular Sciences 2021 Jan; 22(3):1131.
Application：PLA-Ce, WB-Tr, Human, A-549, HEK 293 cells.
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Regulation of the CoA Biosynthetic Complex Assembly in Mammalian Cells.
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