TM6SF2 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TM6SF2 protein.
Immunogen
TM6SF2 (AAI60089.1, 1 a.a. ~ 377 a.a) full-length human protein.
Sequence
MDIPPLAGKIAALSLSALPVSYALNHVSALSHPLWVALMSALILGLLFVAVYSLSHGEVSYDPLYAVFAVFAFTSVVDLIIALQEDSYVVGFMEFYTKEGEPYLRTAHGVFICYWDGTVHYLLYLAMAGAICRRKRYRNFGLYWLGSFAMSILVFLTGNILGKYSSEIRPAFFLTIPYLLVPCWAGMKVFSQPRALTRCTANMVQEEQRKGLLQRPADLALVIYLILAGFFTLFRGLVVLDCPTDACFVYIYQYEPYLRDPVAYPKVQMLMYMFYVLPFCGLAAYALTFPGCSWLPDWALVFAGGIGQAQFSHMGASMHLRTPFTYRVPEDTWGCFFVCNLLYALGPHLLAYRCLQWPAFFHQPPPSDPLALHKKQH
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TM6SF2 expression in transfected 293T cell line by TM6SF2 MaxPab polyclonal antibody.
Lane 1: TM6SF2 transfected lysate(41.47 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TM6SF2
Entrez GeneID
53345GeneBank Accession#
BC160089.1Protein Accession#
AAI60089.1Gene Name
TM6SF2
Gene Alias
KIAA1926
Gene Description
transmembrane 6 superfamily member 2
Omim ID
606563Gene Ontology
HyperlinkOther Designations
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Interactome
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Publication Reference
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TM6SF2 Promotes Lipidation and Secretion of Hepatitis C Virus in Infected Hepatocytes.
Boyer A, Park SB, de Boer Y, Li Q, Liang TJ.
Gastroenterology 2018 Aug; [Epub].
Application:WB, Human, Huh7 cells.
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TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content.
Mahdessian H, Taxiarchis A, Popov S, Silveira A, Franco-Cereceda A, Hamsten A, Eriksson P.
PNAS 2014 Jun; 111(24):8913.
Application:WB-Tr, Human, Huh7, HepG2 cells.
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TM6SF2 Promotes Lipidation and Secretion of Hepatitis C Virus in Infected Hepatocytes.
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