SIRT6 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SIRT6 protein.
Immunogen
SIRT6 (AAH28220.1, 1 a.a. ~ 328 a.a) full-length human protein.
Sequence
MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSNVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76); Rat (75)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SIRT6 expression in transfected 293T cell line (H00051548-T02) by SIRT6 MaxPab polyclonal antibody.
Lane 1: SIRT6 transfected lysate(36.08 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SIRT6
Entrez GeneID
51548GeneBank Accession#
BC028220.1Protein Accession#
AAH28220.1Gene Name
SIRT6
Gene Alias
SIR2L6
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
Omim ID
606211Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq
Other Designations
sir2-related protein type 6|sirtuin 6|sirtuin type 6
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