PHF7 MaxPab mouse polyclonal antibody (B01)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PHF7 protein.
Immunogen
PHF7 (NP_057567.3, 1 a.a. ~ 381 a.a) full-length human protein.
Sequence
MKTVKEKKECQRLRKSAKTRRVTQRKPSSGPVCWLCLREPGDPEKLGEFLQKDNISVHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPCGQERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEESCILCCEDLSQQSVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRDAAWELEPGAFSDLYQRYQHCDAPICLYEQGRDSFEDEGRWCLILCATCGSHGTHRDCSSLRSNSKKWECEECSPAAATDYIPENSGDIPCCSSTFHPEEHFCRDNTLEENPGLSWTDWPEPSLLEKPESSRGRRSYSWRSKGVRITNSCKKSK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
PHF7 MaxPab polyclonal antibody. Western Blot analysis of PHF7 expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of PHF7 expression in transfected 293T cell line (H00051533-T01) by PHF7 MaxPab polyclonal antibody.
Lane 1: PHF7 transfected lysate(41.91 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PHF7
Entrez GeneID
51533GeneBank Accession#
NM_016483.4Protein Accession#
NP_057567.3Gene Name
PHF7
Gene Alias
DKFZp434L1850, HSPC045, HSPC226, MGC26088, NYD-SP6
Gene Description
PHD finger protein 7
Gene Ontology
HyperlinkGene Summary
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq
Other Designations
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Interactome
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