GTSE1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GTSE1 protein.
Immunogen
GTSE1 (NP_057510.2, 1 a.a. ~ 720 a.a) full-length human protein.
Sequence
MDDPKKEDILLLADEKFDFDLSLSSSSANEDDEVFFGPFGHKERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVGQLIDLSSPLIQLSPEADKENVDSPLLKF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (56); Rat (56)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GTSE1 MaxPab polyclonal antibody. Western Blot analysis of GTSE1 expression in human colon.Western Blot (Transfected lysate)
Western Blot analysis of GTSE1 expression in transfected 293T cell line (H00051512-T01) by GTSE1 MaxPab polyclonal antibody.
Lane 1: GTSE1 transfected lysate(79.2 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GTSE1
Entrez GeneID
51512GeneBank Accession#
NM_016426Protein Accession#
NP_057510.2Gene Name
GTSE1
Gene Alias
B99
Gene Description
G-2 and S-phase expressed 1
Omim ID
607477Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq
Other Designations
OTTHUMP00000028851
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Interactome
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Pathway
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Disease
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Publication Reference
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Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension.
Cheeseman LP, Harry EF, McAinsh AD, Prior IA, Royle SJ.
Journal of Cell Science 2013 May; 126(Pt 9):2102.
Application:IF, Human, HeLa cells.
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Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension.
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