PRRX2 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PRRX2 protein.
Immunogen
PRRX2 (NP_057391.1, 1 a.a. ~ 253 a.a) full-length human protein.
Sequence
MDSAAAAFALDKPALGPGPPPPPPALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (87); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PRRX2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PRRX2 expression in mouse brain.Western Blot (Transfected lysate)
Western Blot analysis of PRRX2 expression in transfected 293T cell line (H00051450-T02) by PRRX2 MaxPab polyclonal antibody.
Lane 1: PRRX2 transfected lysate(27.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PRRX2 transfected lysate using anti-PRRX2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PRRX2 purified MaxPab mouse polyclonal antibody (B01P) (H00051450-B01P).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PRRX2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PRRX2
Entrez GeneID
51450GeneBank Accession#
NM_016307.3Protein Accession#
NP_057391.1Gene Name
PRRX2
Gene Alias
MGC19843, PMX2, PRX2
Gene Description
paired related homeobox 2
Omim ID
604675Gene Ontology
HyperlinkGene Summary
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq
Other Designations
OTTHUMP00000022344|paired mesoderm homeobox protein 2|paired-like homeodomain protein PRX2|predicted NUP98/PRRX2 fusion protein
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Disease
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Publication Reference
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Uterine Prx2 restrains decidual differentiation through inhibiting lipolysis in mice.
Jiang Y, Kong S, He B, Wang B, Wang H, Lu J.
Cell and Tissue Research 2016 Mar; 365(2):403.
Application:WB-Ti, Mouse, Mouse uterine tissues.
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Uterine Prx2 restrains decidual differentiation through inhibiting lipolysis in mice.
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