F11R 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
F11R transfected lysate.
Western Blot
Lane 1: F11R transfected lysate ( 32.60 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-F11R full-length
Host
Human
Theoretical MW (kDa)
32.6
Interspecies Antigen Sequence
Mouse (68); Rat (71)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-F11R antibody (H00050848-D01P) by Western Blots.
SDS-PAGE Gel
F11R transfected lysate.
Western Blot
Lane 1: F11R transfected lysate ( 32.60 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — F11R
Entrez GeneID
50848GeneBank Accession#
NM_016946.3Protein Accession#
NP_058642.1Gene Name
F11R
Gene Alias
CD321, JAM, JAM-1, JAM-A, JAM1, JAMA, JCAM, KAT, PAM-1
Gene Description
F11 receptor
Omim ID
605721Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq
Other Designations
OTTHUMP00000027880|OTTHUMP00000027881|junctional adhesion molecule 1|junctional adhesion molecule A|platelet F11 receptor|platelet adhesion molecule
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