F11R purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
F11R MaxPab rabbit polyclonal antibody. Western Blot analysis of F11R expression in mouse brain.
Western Blot (Tissue lysate)
F11R MaxPab rabbit polyclonal antibody. Western Blot analysis of F11R expression in human pancreas.
Western Blot (Cell lysate)
F11R MaxPab rabbit polyclonal antibody. Western Blot analysis of F11R expression in IMR-32.
Western Blot (Transfected lysate)
Western Blot analysis of F11R expression in transfected 293T cell line (H00050848-T02) by F11R MaxPab polyclonal antibody.
Lane 1: F11R transfected lysate(32.60 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human F11R protein.
Immunogen
F11R (NP_058642.1, 1 a.a. ~ 299 a.a) full-length human protein.
Sequence
MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEGEFKQTSSFLV
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (68); Rat (71)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
F11R MaxPab rabbit polyclonal antibody. Western Blot analysis of F11R expression in mouse brain.Western Blot (Tissue lysate)
F11R MaxPab rabbit polyclonal antibody. Western Blot analysis of F11R expression in human pancreas.Western Blot (Cell lysate)
F11R MaxPab rabbit polyclonal antibody. Western Blot analysis of F11R expression in IMR-32.Western Blot (Transfected lysate)
Western Blot analysis of F11R expression in transfected 293T cell line (H00050848-T02) by F11R MaxPab polyclonal antibody.
Lane 1: F11R transfected lysate(32.60 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — F11R
Entrez GeneID
50848GeneBank Accession#
NM_016946.3Protein Accession#
NP_058642.1Gene Name
F11R
Gene Alias
CD321, JAM, JAM-1, JAM-A, JAM1, JAMA, JCAM, KAT, PAM-1
Gene Description
F11 receptor
Omim ID
605721Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq
Other Designations
OTTHUMP00000027880|OTTHUMP00000027881|junctional adhesion molecule 1|junctional adhesion molecule A|platelet F11 receptor|platelet adhesion molecule
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Interactome
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Pathway
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Disease
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