F11R (Human) Matched Antibody Pair
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Sandwich ELISA detection sensitivity ranging from approximately 243x to 3x dilution of the F11R 293T overexpression lysate (non-denatured).
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human F11R.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (71)
Quality Control Testing
Standard curve using F11R 293T overexpression lysate (non-denatured) as an analyte.
Sandwich ELISA detection sensitivity ranging from approximately 243x to 3x dilution of the F11R 293T overexpression lysate (non-denatured).
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-F11R (100 ug)
2. Detection antibody: rabbit MaxPab® affinity purified polyclonal anti-F11R (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Transfected lysate)
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Gene Info — F11R
Entrez GeneID
50848Gene Name
F11R
Gene Alias
CD321, JAM, JAM-1, JAM-A, JAM1, JAMA, JCAM, KAT, PAM-1
Gene Description
F11 receptor
Omim ID
605721Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq
Other Designations
OTTHUMP00000027880|OTTHUMP00000027881|junctional adhesion molecule 1|junctional adhesion molecule A|platelet F11 receptor|platelet adhesion molecule
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Interactome
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Disease
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