LASS2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human LASS2 protein.
Immunogen
LASS2 (NP_071358.1, 1 a.a. ~ 380 a.a) full-length human protein.
Sequence
MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
LASS2 MaxPab polyclonal antibody. Western Blot analysis of LASS2 expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of LASS2 expression in transfected 293T cell line (H00029956-T02) by LASS2 MaxPab polyclonal antibody.
Lane 1: LASS2 transfected lysate(41.8 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — LASS2
Entrez GeneID
29956GeneBank Accession#
NM_022075.2Protein Accession#
NP_071358.1Gene Name
LASS2
Gene Alias
CerS2, FLJ10243, L3, MGC987, SP260, TMSG1
Gene Description
LAG1 homolog, ceramide synthase 2
Omim ID
606920Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
Other Designations
LAG1 longevity assurance 2|OTTHUMP00000033028|ceramide synthase 2|longevity assurance (LAG1, S. cerevisiae) homolog 2|tumor metastasis-suppressor
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Interactome
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Disease
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Publication Reference
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Bcl2L13 is a ceramide synthase inhibitor in glioblastoma.
Jensen SA, Calvert AE, Volpert G, Kouri FM, Hurley LA, Luciano JP, Wu Y, Chalastanis A, Futerman AH, Stegh AH.
PNAS 2014 Apr; 111(15):5682.
Application:WB-Ce, Human, SF767 cells.
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Bcl2L13 is a ceramide synthase inhibitor in glioblastoma.
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