ANGPTL3 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ANGPTL3 full-length
Host
Human
Theoretical MW (kDa)
50.71
Interspecies Antigen Sequence
Mouse (76); Rat (80)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ANGPTL3 antibody (H00027329-B01) by Western Blots.
SDS-PAGE Gel
ANGPTL3 transfected lysate.
Western Blot
Lane 1: ANGPTL3 transfected lysate ( 53.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ANGPTL3
Entrez GeneID
27329GeneBank Accession#
NM_014495Protein Accession#
NP_055310Gene Name
ANGPTL3
Gene Alias
ANGPT5
Gene Description
angiopoietin-like 3
Omim ID
604774Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000010719|angiopoietin 5
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