KLK5 monoclonal antibody (M01), clone 3H3
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KLK5 is 0.3 ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KLK5.
Immunogen
KLK5 (NP_036559, 194 a.a. ~ 293 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (68)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KLK5 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — KLK5
Entrez GeneID
25818GeneBank Accession#
NM_012427Protein Accession#
NP_036559Gene Name
KLK5
Gene Alias
KLK-L2, KLKL2, SCTE
Gene Description
kallikrein-related peptidase 5
Omim ID
605643Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
kallikrein 5|kallikrein-like protein 2|stratum corneum tryptic enzyme
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Interactome
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Disease
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