MAP3K7IP2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of MAP3K7IP2 expression in transfected 293T cell line (H00023118-T01) by MAP3K7IP2 MaxPab polyclonal antibody.
Lane 1: MAP3K7IP2 transfected lysate(76.23 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MAP3K7IP2 protein.
Immunogen
MAP3K7IP2 (NP_055908, 1 a.a. ~ 693 a.a) full-length human protein.
Sequence
MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDLNFSDDSGISGLRNHMTSLNLDLQSQNIYHHGREGSRMNGSRTLTHSISDGQLQGGQSNSELFQQEPQTAPAQVPQGFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVTLAPNIQTGRNTPTSLHIHGVPPPVLNSPQGNSIYIRPYITTPGGTTRQTQQHSGWVSQFNPMNPQQVYQPSQPGPWTTCPASNPLSHTSSQQPNQQGHQTSHVYMPISSPTTSQPPTIHSSGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTLNRNQPTVYIAASPPNTDELMSRSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQKARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNRQLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRSIIKTPKTQDTEDDEGAQWNCTACTFLNHPALIRCEQCEMPRHF
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MAP3K7IP2 expression in transfected 293T cell line (H00023118-T01) by MAP3K7IP2 MaxPab polyclonal antibody.
Lane 1: MAP3K7IP2 transfected lysate(76.23 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MAP3K7IP2
Entrez GeneID
23118GeneBank Accession#
NM_015093Protein Accession#
NP_055908Gene Name
MAP3K7IP2
Gene Alias
FLJ21885, KIAA0733, TAB2
Gene Description
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Omim ID
605101Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq
Other Designations
OTTHUMP00000017388|OTTHUMP00000040125|TAK1-binding protein 2
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Interactome
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Pathway
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Disease
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