PNKP MaxPab mouse polyclonal antibody (B01)
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More Files
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Western Blot (Tissue lysate)
PNKP MaxPab polyclonal antibody. Western Blot analysis of PNKP expression in human spleen.
Western Blot (Transfected lysate)
Western Blot analysis of PNKP expression in transfected 293T cell line (H00011284-T01) by PNKP MaxPab polyclonal antibody.
Lane 1: PNKP transfected lysate(57.31 KDa).
Lane 2: Non-transfected lysate.
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human PNKP protein.
Immunogen
PNKP (NP_009185, 1 a.a. ~ 521 a.a) full-length human protein.
Sequence
MGEVEAPGRLWLESPPGGAPPIFLPSDGQALVLGRGPLTQVTDRKCSRTQVELVADPETRTVAVKQLGVNPSTTGTQELKPGLEGSLGVGDTLYLVNGLHPLTLRWEETRTPESQPDTPPGTPLVSQDEKRDAELPKKRMRKSNPGWENLEKLLVFTAAGVKPQGKVAGFDLDGTLITTRSGKVFPTGPSDWRILYPEIPRKLRELEAEGYKLVIFTNQMSIGRGKLPAEEFKAKVEAVVEKLGVPFQVLVATHAGLYRKPVTGMWDHLQEQANDGTPISIGDSIFVGDAAGRPANWAPGRKKKDFSCADRLFALNLGLPFATPEEFFLKWPAAGFELPAFDPRTVSRSGPLCLPESRALLSASPEVVVAVGFPGAGKSTFLKKHLVSAGYVHVNRDTLGSWQRCVTTCETALKQGKRVAIDNTNPDAASRARYVQCARAAGVPCRCFLFTATLEQARHNNRFREMTDSSHIPVSDMVMYGYRKQFEAPTLAEGFSAILEIPFRLWVEPRLGRLYCQFSEG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (80); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
PNKP MaxPab polyclonal antibody. Western Blot analysis of PNKP expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of PNKP expression in transfected 293T cell line (H00011284-T01) by PNKP MaxPab polyclonal antibody.
Lane 1: PNKP transfected lysate(57.31 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PNKP
Entrez GeneID
11284GeneBank Accession#
NM_007254Protein Accession#
NP_009185Gene Name
PNKP
Gene Alias
PNK
Gene Description
polynucleotide kinase 3'-phosphatase
Omim ID
605610Gene Ontology
HyperlinkOther Designations
Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP)|Polynucleotide kinase 3'-phosphatase, amino acids 68-521|Polynucleotide kinase 3'-phosphatase, partial sequence|polynucleotide kinase 3-prime-phosphatase
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Interactomes
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Diseases
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Publication Reference
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Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability.
Enni Markkanen, Roman Fischer, Marina Ledentcova, Benedikt M Kessler, Grigory L Dianov.
Nucleic Acids Research 2015 Apr; 43(7):3667.
Application：WB-Tr, Human, TIG-1 cells.
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Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability.
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