USP18 MaxPab mouse polyclonal antibody (B01)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human USP18 protein.
Immunogen
USP18 (AAH14896, 1 a.a. ~ 372 a.a) full-length human protein.
Sequence
MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWLCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (70); Rat (70)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
USP18 MaxPab polyclonal antibody. Western Blot analysis of USP18 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of USP18 expression in transfected 293T cell line (H00011274-T01) by USP18 MaxPab polyclonal antibody.
Lane 1: USP18 transfected lysate(41.03 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — USP18
Entrez GeneID
11274GeneBank Accession#
BC014896Protein Accession#
AAH14896Gene Name
USP18
Gene Alias
ISG43, UBP43
Gene Description
ubiquitin specific peptidase 18
Omim ID
607057Gene Ontology
HyperlinkGene Summary
USP18, a member of the deubiquitinating protease family of enzymes, removes ubiquitin adducts from a broad range of protein substrates.[supplied by OMIM
Other Designations
ubiquitin specific protease 18
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Interactome
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Publication Reference
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Smoothened Stabilizes and Protects TRAF6 from Degradation: A Novel Non-Canonical Role of Smoothened with Implications in Lymphoma Biology.
Qu C, Kunkalla K, Vaghefi A, Frederiksen JK, Liu Y, Chapman JR, Blonska M, Bernal-Mizrachi L, Alderuccio JP, Lossos IS, Landgraf R, Vega F.
Cancer Letters 2018 Nov; 436:149.
Application:WB, Human, Diffuse large B cell lymphoma cells.
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Smoothened Stabilizes and Protects TRAF6 from Degradation: A Novel Non-Canonical Role of Smoothened with Implications in Lymphoma Biology.
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