DUSP12 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of DUSP12 expression in transfected 293T cell line (H00011266-T01) by DUSP12 MaxPab polyclonal antibody.
Lane 1: DUSP12 transfected lysate(37.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of DUSP12 transfected lysate using anti-DUSP12 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with DUSP12 purified MaxPab mouse polyclonal antibody (B01P) (H00011266-B01P).
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DUSP12 on HeLa cell. [antibody concentration 20 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DUSP12 protein.
Immunogen
DUSP12 (NP_009171.1, 1 a.a. ~ 340 a.a) full-length human protein.
Sequence
MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREGSGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (82)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DUSP12 expression in transfected 293T cell line (H00011266-T01) by DUSP12 MaxPab polyclonal antibody.
Lane 1: DUSP12 transfected lysate(37.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of DUSP12 transfected lysate using anti-DUSP12 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with DUSP12 purified MaxPab mouse polyclonal antibody (B01P) (H00011266-B01P).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DUSP12 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — DUSP12
Entrez GeneID
11266GeneBank Accession#
NM_007240.1Protein Accession#
NP_009171.1Gene Name
DUSP12
Gene Alias
DUSP1, YVH1
Gene Description
dual specificity phosphatase 12
Omim ID
604835Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq
Other Designations
OTTHUMP00000032494|YVH1 protein-tyrosine phosphatase ortholog|serine/threonine specific protein phosphatase
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Interactome
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Disease
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