MSL3L1 MaxPab mouse polyclonal antibody (B01)
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More Files
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Western Blot (Cell lysate)
MSL3 MaxPab polyclonal antibody. Western Blot analysis of MSL3 expression in NIH/3T3.
Western Blot (Cell lysate)
MSL3L1 MaxPab polyclonal antibody. Western Blot analysis of MSL3L1 expression in RIN-m5F.
Western Blot (Transfected lysate)
Western Blot analysis of MSL3 expression in transfected 293T cell line (H00010943-T01) by MSL3 MaxPab polyclonal antibody.
Lane 1: MSL3L1 transfected lysate(57.31 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MSL3L1 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MSL3L1 protein.
Immunogen
MSL3L1 (AAH31210.1, 1 a.a. ~ 521 a.a) full-length human protein.
Sequence
MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY
Host
Mouse
Reactivity
Human, Mouse, Rat
Interspecies Antigen Sequence
Mouse (86); Rat (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Cell lysate)
MSL3 MaxPab polyclonal antibody. Western Blot analysis of MSL3 expression in NIH/3T3.Western Blot (Cell lysate)
MSL3L1 MaxPab polyclonal antibody. Western Blot analysis of MSL3L1 expression in RIN-m5F.Western Blot (Transfected lysate)
Western Blot analysis of MSL3 expression in transfected 293T cell line (H00010943-T01) by MSL3 MaxPab polyclonal antibody.
Lane 1: MSL3L1 transfected lysate(57.31 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MSL3L1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — MSL3
Entrez GeneID
10943GeneBank Accession#
BC031210.1Protein Accession#
AAH31210.1Gene Name
MSL3
Gene Alias
DKFZp586J1822, MSL3L1
Gene Description
male-specific lethal 3 homolog (Drosophila)
Omim ID
300609Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000022911|OTTHUMP00000022912|drosophila MSL3-like 1|male-specific lethal 3-like 1
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Interactome
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Publication Reference
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A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing.
Kapoor-Vazirani P, Vertino PM.
The Journal of Biological Chemistry 2014 Mar; 289(11):7425.
Application：WB-Ce, Human, MCF-7 cells.
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A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing.
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