PRSS21 monoclonal antibody (M01), clone 2E10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PRSS21.
Immunogen
PRSS21 (NP_006790, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (64); Rat (62)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of PRSS21 transfected lysate using anti-PRSS21 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PRSS21 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PRSS21 is 10 ng/ml as a capture antibody.ELISA
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Gene Info — PRSS21
Entrez GeneID
10942GeneBank Accession#
NM_006799Protein Accession#
NP_006790Gene Name
PRSS21
Gene Alias
ESP-1, ESP1, TEST1, TESTISIN
Gene Description
protease, serine, 21 (testisin)
Omim ID
608159Gene Ontology
HyperlinkGene Summary
This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. It is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and it may be involved in progression of testicular tumors of germ cell origin. Alternative splicing of this gene results in three transcript variants encoding three different isoforms. [provided by RefSeq
Other Designations
serine protease from eosinophils|testisin
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