RUVBL2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RUVBL2 protein.
Immunogen
RUVBL2 (NP_006657.1, 1 a.a. ~ 463 a.a) full-length human protein.
Sequence
MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGETMDTS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
RUVBL2 MaxPab polyclonal antibody. Western Blot analysis of RUVBL2 expression in human pancreas.Western Blot (Cell lysate)
RUVBL2 MaxPab polyclonal antibody. Western Blot analysis of RUVBL2 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of RUVBL2 expression in transfected 293T cell line (H00010856-T01) by RUVBL2 MaxPab polyclonal antibody.
Lane 1: RUVBL2 transfected lysate(50.93 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RUVBL2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — RUVBL2
Entrez GeneID
10856GeneBank Accession#
NM_006666.1Protein Accession#
NP_006657.1Gene Name
RUVBL2
Gene Alias
CGI-46, ECP51, INO80J, REPTIN, RVB2, TIH2, TIP48, TIP49B
Gene Description
RuvB-like 2 (E. coli)
Omim ID
604788Gene Ontology
HyperlinkGene Summary
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq
Other Designations
INO80 complex subunit J|Reptin52|RuvB (E coli homolog)-like 2|RuvB-like 2|TBP-interacting protein, 48-KD|erythrocyte cytosolic protein, 51-KD
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Interactome
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Disease
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Publication Reference
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A Divergent Substrate-Binding Loop within the Pro-oncogenic Protein Anterior Gradient-2 Forms a Docking Site for Reptin.
Maslon MM, Hrstka R, Vojtesek B, Hupp TR.
Journal of Molecular Biology 2010 Oct; 404(3):418.
Application:WB-Ti, Human, Human breast cancer.
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A Divergent Substrate-Binding Loop within the Pro-oncogenic Protein Anterior Gradient-2 Forms a Docking Site for Reptin.
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