MTHFD2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of MTHFD2 expression in transfected 293T cell line (H00010797-T02) by MTHFD2 MaxPab polyclonal antibody.
Lane 1: MTHFD2 transfected lysate(26.80 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MTHFD2 protein.
Immunogen
MTHFD2 (NP_001035499.1, 1 a.a. ~ 248 a.a) full-length human protein.
Sequence
MKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MTHFD2 expression in transfected 293T cell line (H00010797-T02) by MTHFD2 MaxPab polyclonal antibody.
Lane 1: MTHFD2 transfected lysate(26.80 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MTHFD2
Entrez GeneID
10797GeneBank Accession#
NM_001040409.1Protein Accession#
NP_001035499.1Gene Name
MTHFD2
Gene Alias
NMDMC
Gene Description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Omim ID
604887Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq
Other Designations
NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase|methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase|methylene tetrahydrofolate dehydrogenase 2
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Interactome
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Pathway
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Disease
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