ZNF274 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ZNF274.
Immunogen
ZNF274 (NP_598009, 420 a.a. ~ 530 a.a) partial recombinant protein with GST tag.
Sequence
QKIDNPESQANSGALDTNQVLLHKIPPRKRLRKRDSQVKSMKHNSRVKIHQKSCERQKAKEGNGCRKTFSRSTKQITFIRIHKGSQVCRCSECGKIFRNPRYFSVHKKIHT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (41); Rat (39)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.32 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ZNF274
Entrez GeneID
10782GeneBank Accession#
NM_133502Protein Accession#
NP_598009Gene Name
ZNF274
Gene Alias
DKFZp686K08243, FLJ37843, HFB101, ZF2, ZKSCAN19
Gene Description
zinc finger protein 274
Omim ID
605467Gene Ontology
HyperlinkGene Summary
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq
Other Designations
KRAB zinc finger protein HFB101|zinc finger protein zfp2
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Interactome
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Pathway
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Publication Reference
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ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes.
Frietze S, O'Geen H, Blahnik KR, Jin VX, Farnham PJ.
PLoS One 2010 Dec; 5(12):e15082.
Application:ChIP, IP, IP-WB, WB-Tr, WB-Ce, Human, K562, HelaS3, GM12878, HepG2, cells.
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ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes.
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