DCTN2 purified MaxPab mouse polyclonal antibody (B01P)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
DCTN2 MaxPab polyclonal antibody. Western Blot analysis of DCTN2 expression in human spleen.
Western Blot (Transfected lysate)
Western Blot analysis of DCTN2 expression in transfected 293T cell line (H00010540-T01) by DCTN2 MaxPab polyclonal antibody.
Lane 1: DCTN2 transfected lysate(44.11 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DCTN2 on HeLa cell. [antibody concentration 10 ug/ml]
-
Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DCTN2 protein.
Immunogen
DCTN2 (AAH00718.1, 1 a.a. ~ 401 a.a) full-length human protein.
Sequence
MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Tissue lysate)
DCTN2 MaxPab polyclonal antibody. Western Blot analysis of DCTN2 expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of DCTN2 expression in transfected 293T cell line (H00010540-T01) by DCTN2 MaxPab polyclonal antibody.
Lane 1: DCTN2 transfected lysate(44.11 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DCTN2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — DCTN2
Entrez GeneID
10540GeneBank Accession#
BC000718Protein Accession#
AAH00718.1Gene Name
DCTN2
Gene Alias
DCTN50, DYNAMITIN, RBP50
Gene Description
dynactin 2 (p50)
Omim ID
607376Gene Ontology
HyperlinkGene Summary
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq
Other Designations
50 kD dynein-associated polypeptide|dynactin 2|dynactin complex 50 kD subunit
-
Interactome
-
Publication Reference
-
Dynamitin Impacts Cell Surface Expression of Voltage-Gated Sodium Channel Nav1.5.
Chatin B, Colombier P, Gamblin AL, Allouis M, Le Bouffant F.
The Biochemical Journal 2014 Nov; 463(3):339.
Application：IP, Mouse, Heart.
-
Dynamitin Impacts Cell Surface Expression of Voltage-Gated Sodium Channel Nav1.5.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com