Products

Western Blot (Transfected lysate)

Western Blot analysis of CREB3 expression in transfected 293T cell line (H00010488-T02) by CREB3 MaxPab polyclonal antibody.

Lane 1: CREB3 transfected lysate(41.40 KDa).
Lane 2: Non-transfected lysate.

Western Blot (Recombinant protein)

Western Blot analysis of CREB3 recombinant protein (H00010488-P01) by CREB3 purified MaxPab rabbit polyclonal antibody.

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between CREB3 and CREB3L4. HeLa cells were stained with anti-CREB3 rabbit purified polyclonal 1:1200 and anti-CREB3L4 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Entrez GeneID

10488

GeneBank Accession#

BC009402.2

Protein Accession#

AAH09402.1

Gene Name

CREB3

Gene Alias

LUMAN, LZIP, MGC15333, MGC19782

Gene Description

cAMP responsive element binding protein 3

Omim ID

606443

Gene Ontology

Hyperlink

Gene Summary

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq

Other Designations

OTTHUMP00000021348|basic leucine zipper protein|cyclic AMP response element (CRE)-binding protein/activating transcription factor 1|transcription factor LZIP-alpha