TRIM22 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TRIM22 protein.
Immunogen
TRIM22 (NP_006065.2, 1 a.a. ~ 498 a.a) full-length human protein.
Sequence
MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFNPWNCLVPMTVCPPSS
Host
Mouse
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TRIM22 MaxPab polyclonal antibody. Western Blot analysis of TRIM22 expression in Raw 264.7.Western Blot (Transfected lysate)
Western Blot analysis of TRIM22 expression in transfected 293T cell line (H00010346-T01) by TRIM22 MaxPab polyclonal antibody.
Lane 1: TRIM22 transfected lysate(54.78 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TRIM22
Entrez GeneID
10346GeneBank Accession#
BC035582.1Protein Accession#
NP_006065.2Gene Name
TRIM22
Gene Alias
GPSTAF50, RNF94, STAF50
Gene Description
tripartite motif-containing 22
Omim ID
606559Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. [provided by RefSeq
Other Designations
OTTHUMP00000069823|stimulated trans-acting factor (50 kDa)|tripartite binding motif 22|tripartite motif protein TRIM22
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Interactome
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Publication Reference
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HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter.
Turrini F, Marelli S, Kajaste-Rudnitski A, Lusic M, Van Lint C, Das AT, Harwig A, Berkhout B, Vicenzi E.
Retrovirology 2015 Dec; 12(1):104.
Application:IP, Human, HEK 293T cells.
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HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter.
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