CALCOCO2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CALCOCO2 protein.
Immunogen
CALCOCO2 (NP_005822.1, 1 a.a. ~ 446 a.a) full-length human protein.
Sequence
MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLKRENSRLLSYMGLDFNSLPYQVPTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPICKADDICDHTLEQQQMQPLCFNCPICDKIFPATEKQIFEDHVFCHSL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CALCOCO2 MaxPab polyclonal antibody. Western Blot analysis of CALCOCO2 expression in human liver.Western Blot (Tissue lysate)
CALCOCO2 MaxPab polyclonal antibody. Western Blot analysis of CALCOCO2 expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of CALCOCO2 expression in transfected 293T cell line (H00010241-T01) by CALCOCO2 MaxPab polyclonal antibody.
Lane 1: CALCOCO2 transfected lysate(49.06 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CALCOCO2
Entrez GeneID
10241GeneBank Accession#
NM_005831.3Protein Accession#
NP_005822.1Gene Name
CALCOCO2
Gene Alias
MGC17318, NDP52
Gene Description
calcium binding and coiled-coil domain 2
Omim ID
604587Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a subunit of nuclear domain 10 (ND10) bodies. ND10 bodies are nuclear domains appearing immunohistochemically as ten dots per nucleus. They are believed to be associated with the nuclear matrix on the basis of their resistance to nuclease digestion and salt extraction. ND10 proteins are removed from the nucleus by herpes simplex virus-1 infection and may have a role in viral life cycles. [provided by RefSeq
Other Designations
nuclear domain 10 protein
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Interactome
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Publication Reference
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Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy.
Kibrom M Alula, Yaritza Delgado-Deida, Rosemary Callahan, Andreas Till, Lucia Underwood, Winston E Thompson, Rhonda F Souza, Themistocles Dassopoulos, Joseph Onyiah, K Venuprasad, Arianne L Theiss.
Scientific Reports 2023 Jan; 13(1):18.
Application:WB-Ce, Mouse, Mouse intestinal epithelial cells.
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Coordinate regulation of the senescent state by selective autophagy.
Yeonghyeon Lee, Jaejin Kim, Mi-Sung Kim, Yoojin Kwon, Sanghee Shin, Hyerim Yi, Hyeonkyeong Kim, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang, V Narry Kim, Jin-Hong Kim, Jong-Seo Kim, Stephen J Elledge, Chanhee Kang.
Developmental Cell 2021 May; 56(10):1512.
Application:WB-Tr, Human, Human fibroblasts.
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Transbilayer Movement of Sphingomyelin Precedes Catastrophic Breakage of Enterobacteria-Containing Vacuoles.
Cara J Ellison, Wanda Kukulski, Keith B Boyle, Sean Munro, Felix Randow.
Current Biology : CB 2020 Aug; 30(15):2974.
Application:IF, Human, HeLa cells.
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The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria.
Ravenhill BJ, Boyle KB, von Muhlinen N, Ellison CJ, Masson GR, Otten EG, Foeglein A, Williams R, Randow F.
Molecular Cell 2019 Apr; 74(2):320.
Application:IF, WB, Human, HEK 293T, HeLa cells.
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Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy.
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