RASGRP2 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant RASGRP2.
Immunogen
RASGRP2 (NP_005816, 65 a.a. ~ 164 a.a) partial recombinant protein with GST tag.
Sequence
GTLDLDKGCTVEELLRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLAAKLLHIYQQSRKDNSNSLQVKTCHLVRYWISAFPAEFDLNPELAEQIKE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
RASGRP2 polyclonal antibody (A01), Lot # NIH47060208QCS1 Western Blot analysis of RASGRP2 expression in A-431 ( Cat # L015V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — RASGRP2
Entrez GeneID
10235GeneBank Accession#
NM_005825Protein Accession#
NP_005816Gene Name
RASGRP2
Gene Alias
CALDAG-GEFI, CDC25L
Gene Description
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
Omim ID
605577Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000042931|OTTHUMP00000069245|OTTHUMP00000069246|RAS guanyl nucleotide-releasing protein 2|RAS guanyl releasing protein 2|calcium and DAG-regulated guanine nucleotide exchange factor I|calcium and diacylglycerol-regulated guanine nucleotide exchan
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Interactome
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Pathway
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