SLC25A13 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SLC25A13 partial ORF ( NP_055066, 2 a.a. - 80 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.43
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLC25A13
Entrez GeneID
10165GeneBank Accession#
NM_014251Protein Accession#
NP_055066Gene Name
SLC25A13
Gene Alias
ARALAR2, CITRIN, CTLN2
Gene Description
solute carrier family 25, member 13 (citrin)
Gene Ontology
HyperlinkGene Summary
This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
mitochondrial aspartate glutamate carrier 2
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Interactome
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Disease
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