ABCB6 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ABCB6 partial ORF ( NP_005680, 743 a.a. - 842 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIVVAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTMER
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ABCB6
Entrez GeneID
10058GeneBank Accession#
NM_005689Protein Accession#
NP_005680Gene Name
ABCB6
Gene Alias
ABC, ABC14, EST45597, FLJ22414, MTABC3, PRP, umat
Gene Description
ATP-binding cassette, sub-family B (MDR/TAP), member 6
Omim ID
605452Gene Ontology
HyperlinkGene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. [provided by RefSeq
Other Designations
ATP-binding cassette half-transporter|ATP-binding cassette, sub-family B, member 6
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Interactome
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