PDCD6IP MaxPab mouse polyclonal antibody (B02)
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More Files
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Western Blot (Tissue lysate)
PDCD6IP MaxPab polyclonal antibody. Western Blot analysis of PDCD6IP expression in human stomach.
Western Blot (Transfected lysate)
Western Blot analysis of PDCD6IP expression in transfected 293T cell line (H00010015-T01) by PDCD6IP MaxPab polyclonal antibody.
Lane 1: PDCD6IP transfected lysate(95.48 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PDCD6IP protein.
Immunogen
PDCD6IP (NP_037506, 1 a.a. ~ 868 a.a) full-length human protein.
Sequence
MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKERWQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
PDCD6IP MaxPab polyclonal antibody. Western Blot analysis of PDCD6IP expression in human stomach.Western Blot (Transfected lysate)
Western Blot analysis of PDCD6IP expression in transfected 293T cell line (H00010015-T01) by PDCD6IP MaxPab polyclonal antibody.
Lane 1: PDCD6IP transfected lysate(95.48 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PDCD6IP
Entrez GeneID
10015GeneBank Accession#
NM_013374Protein Accession#
NP_037506Gene Name
PDCD6IP
Gene Alias
AIP1, Alix, DRIP4, HP95, MGC17003
Gene Description
programmed cell death 6 interacting protein
Omim ID
608074Gene Ontology
HyperlinkGene Summary
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ALG-2 interacting protein 1|ALG-2 interacting protein X|apoptosis-linked gene 2-interacting protein X|dopamine receptor interacting protein 4|programmed cell death 6-interacting protein
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Interactome
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Pathway
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Disease
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Publication Reference
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UBL3 modification influences protein sorting to small extracellular vesicles.
Ageta H, Ageta-Ishihara N, Hitachi K, Karayel O, Onouchi T, Yamaguchi H, Kahyo T, Hatanaka K, Ikegami K, Yoshioka Y, Nakamura K, Kosaka N, Nakatani M, Uezumi A, Ide T, Tsutsumi Y, Sugimura H, Kinoshita M, Ochiya T, Mann M, Setou M, Tsuchida K.
Nature Communications 2018 Sep; 9(1):3936.
Application：WB-Tr, Human, MDA-MB-231 cells.
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UBL3 modification influences protein sorting to small extracellular vesicles.
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