SLC12A6 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SLC12A6 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SLC12A6 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SLC12A6 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SLC12A6
Entrez GeneID
9990GeneBank Accession#
SLC12A6Gene Name
SLC12A6
Gene Alias
ACCPN, DKFZp434D2135, KCC3, KCC3A, KCC3B
Gene Description
solute carrier family 12 (potassium/chloride transporters), member 6
Gene Ontology
HyperlinkGene Summary
This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq
Other Designations
potassium chloride cotransporter 3|potassium chloride cotransporter KCC3a-S3|solute carrier family 12, member 6
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