ECE2 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human ECE2 full-length ORF ( NP_115707.1, 1 a.a. - 255 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARYAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRTRHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKLSVAQLALGAQILSPPRPPTSPCFLQDSDHEDFLSAIQL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
54.7
Interspecies Antigen Sequence
Mouse (84); Rat (32)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ECE2
Entrez GeneID
9718GeneBank Accession#
NM_032331.2Protein Accession#
NP_115707.1Gene Name
ECE2
Gene Alias
KIAA0604, MGC17664, MGC2408, MGC78487
Gene Description
endothelin converting enzyme 2
Omim ID
610145Gene Ontology
HyperlinkGene Summary
Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 [PubMed 11718899]).[supplied by OMIM
Other Designations
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Interactome
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Disease
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