CLCA2 monoclonal antibody (M01), clone 1B9
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More Files
- More Functions
Western Blot detection against Immunogen (36.85 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CLCA2.
Immunogen
CLCA2 (NP_006527, 300 a.a. ~ 400 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PTFSLVQAGDKVVCLVLDVSSKMAEADRLLQLQQAAEFYLMQIVEIHTFVGIASFDSKGEIRAQLHQINSNDDRKLLVSYLPTTVSAKTDISICSGLKKGF
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.85 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CLCA2
Entrez GeneID
9635GeneBank Accession#
NM_006536Protein Accession#
NP_006527Gene Name
CLCA2
Gene Alias
CACC, CACC3, CLCRG2, CaCC-3, FLJ97885
Gene Description
chloride channel regulator 2
Omim ID
604003Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. [provided by RefSeq
Other Designations
CLCA family member 2, chloride channel regulator|OTTHUMP00000011911|calcium-activated chloride channel protein 3|calcium-activated chloride channel-2|chloride channel, calcium activated, family member 2
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Interactome
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Pathway
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Disease
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