CLOCK (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CLOCK partial ORF ( NP_004889, 497 a.a. - 596 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
PVMSQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPIN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (94); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CLOCK
Entrez GeneID
9575GeneBank Accession#
NM_004898Protein Accession#
NP_004889Gene Name
CLOCK
Gene Alias
KAT13D, KIAA0334, bHLHe8
Gene Description
clock homolog (mouse)
Omim ID
601851Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1. [provided by RefSeq
Other Designations
OTTHUMP00000128334|circadian locomoter output cycles kaput protein|clock
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Interactome
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