BAG2 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of BAG2 transfected lysate using rabbit polyclonal anti-BAG2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-BAG2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (92)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of BAG2 transfected lysate using rabbit polyclonal anti-BAG2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-BAG2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-BAG2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-BAG2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — BAG2
Entrez GeneID
9532Gene Name
BAG2
Gene Alias
BAG-2, KIAA0576, MGC149462, dJ417I1.2
Gene Description
BCL2-associated athanogene 2
Omim ID
603882Gene Ontology
HyperlinkGene Summary
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq
Other Designations
BAG-family molecular chaperone regulator-2|OTTHUMP00000016668|dJ417I1.2 (BAG-family molecular chaperone regulator 2)
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