ADAMTS3 monoclonal antibody (M08A), clone 1D6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ADAMTS3.
Immunogen
ADAMTS3 (NP_055058.1, 1048 a.a. ~ 1128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ESCSKRSSTLPPPYLLEAAETHDDVISNPSDLPRSLVMPTSLVPYHSETPAKKMSLSSISSVGGPNAYAAFRPNSKPDGAN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (22)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.65 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ADAMTS3 monoclonal antibody (M08A), clone 1D6. Western Blot analysis of ADAMTS3 expression in Jurkat.Western Blot (Recombinant protein)
ELISA
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Gene Info — ADAMTS3
Entrez GeneID
9508GeneBank Accession#
NM_014243Protein Accession#
NP_055058.1Gene Name
ADAMTS3
Gene Alias
ADAMTS-4, KIAA0366
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 3
Omim ID
605011Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq
Other Designations
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3|zinc metalloendopeptidase
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Interactome
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Disease
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