HOMER2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human HOMER2 protein.
Immunogen
HOMER2 (NP_004830.2, 1 a.a. ~ 343 a.a) full-length human protein.
Sequence
MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN
Host
Mouse
Reactivity
Human, Rat
Interspecies Antigen Sequence
Mouse (91); Rat (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
HOMER2 MaxPab polyclonal antibody. Western Blot analysis of HOMER2 expression in rat brain.Western Blot (Transfected lysate)
Western Blot analysis of HOMER2 expression in transfected 293T cell line (H00009455-T01) by HOMER2 MaxPab polyclonal antibody.
Lane 1: HOMER2 transfected lysate(37.73 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — HOMER2
Entrez GeneID
9455GeneBank Accession#
NM_004839.2Protein Accession#
NP_004830.2Gene Name
HOMER2
Gene Alias
ACPD, CPD, HOMER-2, HOMER2A, HOMER2B, Vesl-2
Gene Description
homer homolog 2 (Drosophila)
Omim ID
604799Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein may be involved in cell growth. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
cupidin|homer 2|homer homolog 3|homer, neuronal immediate early gene, 2
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Interactome
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Disease
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Publication Reference
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CaMKII modulates diacylglycerol lipase-α activity in the rat nucleus accumbens after incubation of cocaine craving.
Conor H Murray, Andrew D Gaulden, Alex B Kawa, Mike Milovanovic, Aaron J Caccamise, Jonathan R Funke, Sachin Patel, Marina E Wolf.
eNeuro 2021 Oct; 8(5).
Application:WB-Ti, Rat, Rat nucleus accumbens.
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mGlu5 function in the nucleus accumbens core during the incubation of methamphetamine craving.
Conor H Murray, Daniel T Christian, Mike Milovanovic, Jessica A Loweth, Eun-Kyung Hwang, Aaron J Caccamise, Jonathan R Funke, Marina E Wolf.
Neuropharmacology 2021 Jan; 186:108452.
Application:WB-Ti, Rat, Rat brain, Rat nucleus accumbens.
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AAMPA receptor and metabotropic glutamate receptor 1 adaptations in the nucleus accumbens core during incubation of methamphetamine craving.
Murray CH, Loweth JA, Milovanovic M, Stefanik MT, Caccamise AJ, Dolubinzo H, Funke JR, Foster Olive M, Wolf ME.
Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 2019 Aug; 44(9):1534.
Application:WB-Ti, Rat, Rat brains.
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mGluR5 upregulation and the effects of repeated methamphetamine administration and withdrawal on the rewarding efficacy of ketamine and social interaction.
Liao YH, Wang YH, Sun LH, Deng WT, Lee HT, Yu L.
Toxicology and Applied Pharmacology 2018 Dec; 360:58.
Application:WB-Ti, Mouse, Mouse brains.
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Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving.
Loweth JA, Scheyer AF, Milovanovic M, Lacrosse AL, Flores-Barrera E, Werner CT, Li X, Ford KA, Le T, Olive MF, Szumlinski KK, Tseng KY, Wolf ME.
Nature Neuroscience 2014 Jan; 17(1):73.
Application:WB-Ti, Rat, Nucleus accumbens.
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CaMKII modulates diacylglycerol lipase-α activity in the rat nucleus accumbens after incubation of cocaine craving.
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