SOCS6 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SOCS6 expression in transfected 293T cell line (H00009306-T01) by SOCS6 MaxPab polyclonal antibody.
Lane 1: SOCS6 transfected lysate(58.85 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SOCS6 protein.
Immunogen
SOCS6 (NP_004223.2, 1 a.a. ~ 535 a.a) full-length human protein.
Sequence
MKKISLKTLRKSFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGEDEKGGKNRSKSESLMGTLKRRLSAKQKSKGKAGTPSGSSADEDTFSSSSAPIVFKDVRAQRPIRSTSLRSHHYSPAPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQSETTCQEQANSLKSSASHNGDLHLHLDEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSYCLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSPRAGHDDVPPLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFDPNSAPGVARVYDSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SOCS6 expression in transfected 293T cell line (H00009306-T01) by SOCS6 MaxPab polyclonal antibody.
Lane 1: SOCS6 transfected lysate(58.85 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SOCS6
Entrez GeneID
9306GeneBank Accession#
NM_004232Protein Accession#
NP_004223.2Gene Name
SOCS6
Gene Alias
CIS4, HSPC060, SOCS4, SSI4, STAI4, STATI4
Gene Description
suppressor of cytokine signaling 6
Omim ID
605118Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq
Other Designations
STAT induced STAT inhibitor-4|cytokine-inducible SH2 protein 4|suppressor of cytokine signaling 4
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Interactome
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Disease
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