Products

Western Blot (Transfected lysate)

Western Blot analysis of MAP3K14 expression in transfected 293T cell line (H00009020-T02) by MAP3K14 MaxPab polyclonal antibody.

Lane 1: MAP3K14 transfected lysate(104.00 KDa).
Lane 2: Non-transfected lysate.

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between MAP3K14 and CHUK. HeLa cells were stained with anti-MAP3K14 rabbit purified polyclonal 1:1200 and anti-CHUK mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Immunofluorescence

Immunofluorescence of purified MaxPab antibody to MAP3K14 on HeLa cell. [antibody concentration 10 ug/ml]

Entrez GeneID

9020

GeneBank Accession#

BC035576.1

Protein Accession#

NP_003945.2

Gene Name

MAP3K14

Gene Alias

FTDCR1B, HS, HSNIK, NIK

Gene Description

mitogen-activated protein kinase kinase kinase 14

Omim ID

604655

Gene Ontology

Hyperlink

Gene Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq

Other Designations

serine/threonine protein-kinase