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TOP3B 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00008940-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TOP3B full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 96.7
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TOP3B antibody (H00008940-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00008940-T01
    TOP3B transfected lysate.
    Western Blot
    QC Testing of H00008940-T01
    Lane 1: TOP3B transfected lysate ( 96.7 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8940
  • Gene Name:
  • TOP3B
  • Gene Alias:
  • FLJ39376
  • Gene Description:
  • topoisomerase (DNA) III beta
  • Gene Summary:
  • This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. [provided by RefSeq
  • Other Designations:
  • topoisomerase III beta
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