SNURF MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SNURF protein.
Immunogen
SNURF (AAH24777, 1 a.a. ~ 240 a.a) full-length human protein.
Sequence
MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SNURF expression in transfected 293T cell line (H00008926-T01) by SNURF MaxPab polyclonal antibody.
Lane 1: SNURF transfected lysate(26.51 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SNURF on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SNURF
Entrez GeneID
8926GeneBank Accession#
BC024777Protein Accession#
AAH24777Gene Name
SNURF
Gene Alias
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Gene Description
SNRPN upstream reading frame
Gene Ontology
HyperlinkGene Summary
This gene encodes a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known. [provided by RefSeq
Other Designations
SNRPN upstream reading frame protein
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