TNFRSF11A monoclonal antibody (M39), clone 2G2
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More Files
- More Functions
Western Blot (Cell lysate)
TNFRSF11A monoclonal antibody (M39), clone 2G2. Western Blot analysis of TNFRSF11A expression in K-562.
Western Blot (Cell lysate)
TNFRSF11A monoclonal antibody (M39), clone 2G2. Western Blot analysis of TNFRSF11A expression in Raw 264.7.
Western Blot (Cell lysate)
TNFRSF11A monoclonal antibody (M39), clone 2G2. Western Blot analysis of TNFRSF11A expression in PC-12.
Western Blot (Transfected lysate)
Western Blot analysis of TNFRSF11A expression in transfected 293T cell line by TNFRSF11A monoclonal antibody (M39), clone 2G2.
Lane 1: TNFRSF11A transfected lysate (Predicted MW: 67.76 KDa).
Lane 2: Non-transfected lysate.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TNFRSF11A is 0.03 ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TNFRSF11A.
Immunogen
TNFRSF11A (NP_003830.1, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
APPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRN
Host
Mouse
Reactivity
Human, Mouse, Rat
Interspecies Antigen Sequence
Mouse (79); Rat (80)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TNFRSF11A monoclonal antibody (M39), clone 2G2. Western Blot analysis of TNFRSF11A expression in K-562.Western Blot (Cell lysate)
TNFRSF11A monoclonal antibody (M39), clone 2G2. Western Blot analysis of TNFRSF11A expression in Raw 264.7.Western Blot (Cell lysate)
TNFRSF11A monoclonal antibody (M39), clone 2G2. Western Blot analysis of TNFRSF11A expression in PC-12.Western Blot (Transfected lysate)
Western Blot analysis of TNFRSF11A expression in transfected 293T cell line by TNFRSF11A monoclonal antibody (M39), clone 2G2.
Lane 1: TNFRSF11A transfected lysate (Predicted MW: 67.76 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TNFRSF11A is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — TNFRSF11A
Entrez GeneID
8792GeneBank Accession#
NM_003839.1Protein Accession#
NP_003830.1Gene Name
TNFRSF11A
Gene Alias
CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
Gene Description
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells. [provided by RefSeq
Other Designations
loss of heterozygosity, 18, chromosomal region 1|osteoclast differentiation factor receptor|receptor activator of nuclear factor-kappa B|tumor necrosis factor receptor superfamily, member 11a|tumor necrosis factor receptor superfamily, member 11a, activat
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Interactome
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Pathway
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Disease
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